Brady and Brees’ professional careers began only a year apart. Brady, a product of Michigan University, was drafted infamously late with the 199th pick in the 6th round of the 2000 NFL draft by the New England Patriots. You can watch him cry about it in this clip. Brees, a product of Big Ten rival Purdue, was drafted with the 32nd pick in the 2nd round of the 2001 NFL draft by the San Diego Chargers.
Brady stands 6-foot-4 and 225-lbs, while Brees barely makes 6-foot and 209-lbs. Brady has played in 237 games over 18 seasons which averages to 13.2 games played per season. Aside from riding the bench as a rookie through the first game in 2001, 15 games in 2008 to an ACL tear, and 4 games in 2016 to league mandated suspension, Brady has played all 16 games of every season of his career.
Brees has played in 233 games over 17 seasons which averages to 13.7 games played per season. Brees has played in all 16 games in 11 seasons, while playing in 15 another three. Both quarterbacks have been the picture of health, availability, and consistency over their respective tenures.
Since joining the Saints in 2006, Brees has thrown for more yards than Brady in every season except two (2007, 2009), including passing for over 5,000 yards in 5 seasons compared to Brady’s one season hitting that elusive mark. Over their entire careers, Brees has passed for 4,529 more yards than Brady, while also averaging 23.9 more yards per game than the chin-dippled one. “Tom Brady is far less likely to suffer an injury that will keep him from performing at the 4,000- to 4,500-yard level he's been at. Drew Brees has a gunslinger mentality and depends on athleticism to play at a high level. Despite 5,000-plus yards being the standard for him, Brees is exposed to more hits that we don't see Brady take. To end Brady's career, you're going to have to end him physically, but it's so hard to get to him because he manipulates a four-by-four pocket better than anyone I've ever seen.
Because of their different styles, Brees might have two or three years left, while Brady might have four to six. I'm going with Brady on this one.”said by Heath Evans from NFL.com.